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Dietary Supplement GABA Helps Prevent, Treat Type 2 Diabetes In Mouse Study

September 22, 2011: 12:00 AM EST
A U.S. study in mice has determined that the over-the-counter dietary supplement GABA, a naturally-produced amino acid, may have potential to prevent and treat type 2 diabetes. For the study, GABA was given orally to mice that were obese, insulin resistant and in the early stages of type 2 diabetes. GABA was found to prevent disease progression and improve glucose tolerance and insulin sensitivity by suppressing the inflammatory immune responses involved in development of type 2 diabetes. In the future, GABA supplements may become part of a course of treatment for obesity-related type 2 diabetes and metabolic syndrome, the researchers suggested.
Jide Tian, et al., "Combining Antigen-Based Therapy with GABA Treatment Synergistically Prolongs Survival of Transplanted ß-Cells in Diabetic NOD Mice", PLoS ONE, September 22, 2011, © Tian, et al. (open access)
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