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High Protein Diet Shrinks Brains Of Mice In Alzheimer’s Study

October 21, 2009: 01:58 AM EST
Mice fed a high protein diet were found to have smaller brains, according to an international study whose main purpose was to test the effects of a low-calorie, low-fat diet rich in vegetables, fruits, and fish on the progression of Alzheimer’s disease. The research team tested four different menus on a mouse model of Alzheimer’s. Unexpectedly, the brains of the mice fed a high protein/low carb diet were five percent lighter than the others. The researchers were not sure whether the loss of brain mass was associated with Alzheimer’s-type plaque in the brains.
Steve Pedrini , Carlos Thomas , Hannah Brautigam , James Schmeidler , Lap Ho , Paul Fraser , David Westaway , Peter St George Hyslop , Ralph N Martins , Joseph D Buxbaum , Giulio M Pasinetti , Dara L Dickstein , Patrick R Hof , Michelle E Ehrlich, et al., "Dietary composition modulates brain mass and amyloid beta levels in a mouse model of aggressive Alzheimer's amyloid pathology", Molecular Neurodegeneration 2009, October 21, 2009, © BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media.
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