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Uterine Fibroids May Someday Be Treated With Green Tea Compounds

January 14, 2010: 09:30 PM EST
A green tea extract known as epigallocatechin gallate (EGCG) has been shown to kill human leiomyoma cells in lab rat cancer tissue and in fibroid lesions in mice models, suggesting that it might be useful in treating uterine fibroids in humans. Affecting forty percent of reproductive age women, the symptoms of uterine fibroids include excessive vaginal bleeding, anemia, fatigue and lack of energy. In the study, rat leiomyoma cells were treated with various concentrations of EGCG. In the live mice, the treatment “dramatically reduced the volume and weight of tumors at four and eight weeks after the treatment,” researchers said.
Dong Zhang, MD, Mohamed Al-Hendy, Gloria Richard-Davis, MD, Valerie Montgomery-Rice, MD, Chakradhari Sharan, PhD, Veera Rajaratnam, PhD, Anjali Khurana, BS, Ayman Al-Hendy, MD, PhD, "Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice", American Journal of Obstetrics and Gynecology, January 14, 2010, © Mosby, Inc.
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