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Vitamin D Deficiency Associated With Severe Asthma In Children

September 22, 2011: 12:00 AM EST
The findings of a British clinical study of children with severe therapy-resistant asthma (STRA) suggest that vitamin D supplementation may provide a new approach to therapy. Eighty-six children were enrolled in the study, 36 children of whom had STRA, 26 had moderate asthma and 24 had no asthma. The researchers measured the relationships between vitamin D levels and lung function, medication usage and symptom severity. Children with STRA had significantly lower levels of vitamin D, worse symptoms, greater use of asthma medications and poorer lung function than the other children. "Our results suggest that detecting vitamin D deficiency in children with STRA, and then treating that deficiency, may help prevent or reduce” lung damage, the authors concluded.
A. Gupta, et al., "Relationship Between Serum Vitamin D, Disease Severity and Airway Remodeling in Children with Asthma", American Journal of Respiratory and Critical Care Medicine, September 22, 2011, © American Thoracic Society
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