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Compound Similar To Glucosamine Suppresses MS Symptoms In Mouse Study
September 29, 2011: 12:00 AM EST
Researchers at the University of California have discovered in a mouse study that a sugar-based compound similar to the popular dietary supplement glucosamine suppresses the damaging autoimmune response seen in multiple sclerosis. Mouse models of an MS-like autoimmune disease were fed oral N-acetylglucosamine (GlcNAc). The compound inhibited the growth and function of abnormal T-cells that in MS erroneously direct the immune system to attack and break down central nervous system tissue that insulates nerves. The autoimmune response was suppressed, reversing the progression to paralysis. Researchers cautioned consumers that more human studies are required to assess the full potential of the GlcNAc and people who purchase over-the-counter GlcNAc should consult with their doctors before use.
Ani Grigorian, et al., "N-Acetylglucosamine Inhibits T-Helper 1 (Th1) / T-Helper 17 (Th17) Responses And Treats Experimental Autoimmune Encephalomyelitis",
The Journal of Biological Chemistry
, September 29, 2011, © American Society for Biochemistry and Molecular Biology
See also:
http://www.medicalnewstoday.com/articles/235318.php
http://www.upi.com/Health_News/2011/09/30/Amino-sugar-may-help-treat-MS-symptoms/UPI-60511317427962/?spt=hs∨=hn
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