|
The findings of a British clinical study of children with severe therapy-resistant asthma (STRA) suggest that vitamin D supplementation may provide a new approach to therapy. Eighty-six children were enrolled in the study, 36 children of whom had STRA, 26 had moderate asthma and 24 had no asthma. The researchers measured the relationships between vitamin D levels and lung function, medication usage and symptom severity. Children with STRA had significantly lower levels of vitamin D, worse symptoms, greater use of asthma medications and poorer lung function than the other children. "Our results suggest that detecting vitamin D deficiency in children with STRA, and then treating that deficiency, may help prevent or reduce” lung damage, the authors concluded.
"Relationship Between Serum Vitamin D, Disease Severity and Airway Remodeling in Children with Asthma", American Journal of Respiratory and Critical Care Medicine, September 22, 2011
A U.S. study verifies the long-held assumption that zinc plays an important role in controlling communication between neurons in the brain, but researchers warn that people taking zinc supplements should use caution. Zinc supplements are sold without prescription to treat various brain disorders, including depression. But scientists aren’t sure if the supplements modify zinc content in the brain or modify communication efficiency between neurons. In the hippocampus – where learning and memory processes occur – disrupted communication may contribute to epilepsy. The researchers caution that people taking zinc supplements should be careful until there is enough information about desired zinc concentrations and how oral supplements affect them.
"Vesicular Zinc Promotes Presynaptic and Inhibits Postsynaptic Long-Term Potentiation of Mossy Fiber-CA3 Synapse", Neuron, September 21, 2011
An as-yet unpublished study to be presented at a medical meeting in Europe has found an association between consuming low-fat yogurt during pregnancy and childhood asthma and hay fever (allergic rhinitis). The study’s purpose was to determine whether the fatty acids in milk and dairy products consumed during pregnancy protected children from developing allergic diseases. Data from patient registries and questionnaires were analyzed by the researchers. The results showed that drinking milk during pregnancy did not increase the risk of asthma and actually protected against asthma development. But women who ate low-fat yogurt with fruit once a day were 1.6-times more likely to have children who developed asthma by age seven.
"Low-Fat Yogurt Intake When Pregnant May Lead to Child Asthma and Hay Fever, Study Suggests", Press release, presentation at the European Respiratory Society's Annual Congress, September 17, 2011
A Dutch study has found that consumption of fruits and vegetables with white flesh may prevent the incidence of stroke. For the study, researchers examined the association between consumption of fruits and vegetables in various color groups – green, orange/yellow, red/purple and white – with stroke incidence over ten years among 20,069 adults. The participants were free of cardiovascular disease at the start of the study, but 233 eventually suffered strokes. Green, orange/yellow and red/purple fruits and vegetables weren't related to stroke, researchers found. But the risk of stroke dropped by 52 percent for those who ate a lot of white fruits and vegetables – such as apples, pears and cauliflower. They found that each 25-gram-per-day increase in white fruits and vegetable consumption lowered the risk of stroke by nine percent.
"Colors of Fruit and Vegetables and 10-Year Incidence of Stroke", Stroke, September 16, 2011
After studying scientific findings on the health benefits of hydroxytyrosol, an orthodiphenol found in olives and olive oil, the European Food Safety Authority has issued a scientific opinion stating that the ingredient does protect blood lipids from oxidative damage. The EFSA approved the health claims of the product Hytolive, which has a high concentration of natural hydroxytyrosol. The agency based its opinion on the results of three studies that showed a “dose dependent and significant effect of olive oil hydroxytyrosol … on lowering levels of oxidized low density lipoproteins (LDL)” after three weeks of consumption. The EFSA said consuming five mg a day of the ingredient would qualify for an approved health claim.
"EFSA Panel Approves Hydroxytyrosol for Heart-Health Claims", Nutrition Horizon, September 13, 2011
A study conducted in Japan in rats has found that a diet rich in carbohydrates derived from pure maple syrup improved liver function. The rats were fed diets that included either 20 percent pure maple syrup or 20 percent syrup mixture with similar sugar content as maple syrup. After 11 days, the researchers analyzed standard biomarkers for liver function, finding that the rats on the maple syrup diet showed significantly decreased levels of liver enzymes AST, ALT and LDH in the blood. Using a gene expression profiling technique known as nutrigenomics, they found that the maple syrup diet triggers a mechanism that causes genes involved in the production of harmful ammonia in the liver to be less active. The researcher suggested that this beneficial effect may be due to maple syrup’s polyphenolic antioxidants and vitamins and minerals.
"Researchers uncover a potential new benefit of pure maple syrup on liver health", Press release, University of Tokyo, September 13, 2011
Researchers in Australia and Switzerland report that vitamins added to probiotic formulations can either enhance or harm the bacteria, depending on the vitamin used. Blending vitamin E, or tocopherol, in probiotic formulas enhances the viability of bacteria, while vitamin C has a harmful effect. Researchers tested micro-encapsulated probiotic formulations that used Lactobacillus rhamnosus. They mixed in tocopherol, sodium ascorbate (vitamin C), or both, finding that the antioxidant activity of the tocopherol enhanced the probiotics during storage. But the vitamin C salt, even with tocopheral added, “had detrimental effects on probiotic survival.” They concluded that “the chemical effects of additives and their metabolic fate in the presence of probiotic bacteria” need to be monitored when preparing probiotic products.
"Tocopherol and Ascorbate Have Contrasting Effects on the Viability of Microencapsulated Lactobacillus rhamnosus GG", Journal of Agricultural and Food Chemistry, August 15, 2011
Indian researchers who looked at the impact of dietary vitamin A on the activity of an enzyme that controls glucose metabolism have found that the vitamin reduced abdominal fat and overall body weight in obese rats. The animals in the study were fed either a vitamin A-enriched diet or a standard diet. At the end of the experiment, the researchers found that the vitamin A diet “significantly decreased body weight, visceral fat mass and 11b-HSD1 [the enzyme] activity in visceral fat of the obese rats.” The researchers suggested that further research is needed to understand how 11b-HSD1 activity is regulated by nutrients like vitamin A. The results of that research may lead to development of dietary therapies to prevent obesity and insulin resistance.
"Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats", Nutrition Journal, June 23, 2011
Researchers in Hong Kong and Singapore have found that grape seed and clove bud extracts seem to cut the formation of the carcinogen acrylamide in food products made from potatoes by 60 percent. Grape seed compounds known as proanthocyanidins reduced acrylamide production by 62.2 percent in potato-based foods. However, in toher carbohydrate-based foods, such as cookies, extracts of clove buds reduced acrylamide development by 51 percent. Acrylamide is produced when sugar and the amino acid asparagine are subjected to heat. The process, known as the Maillard reaction, results in the brown color of baked, friend or toasted foods. The compound, however, was found to cause cancer in laboratory rats.
"Dietary plant materials reduce acrylamide formation in cookie and starch-based model systems", Journal of the Science of Food and Agriculture, June 16, 2011
|
Pediatric Research, October 01, 2011
Nutraceutical World, September 19, 2011
EurekAlert, September 18, 2011
Iowa State University, September 15, 2011
American Stroke Association, September 15, 2011
Nutrition Research, August 02, 2011
International Journal of Food Science & Technology, July 26, 2011
Pharmacological Research, July 06, 2011
|